4yln_F : 3D-footprint complex

structure name	E. COLI TRANSCRIPTION INITIATION COMPLEX - 17-BP SPACER AND 4-NT RNA (RNA POLYMERASE SIGMA FACTOR RPOD)
reference	Steitz et al. Mol.Cell 58 534 2015
source	ESCHERICHIA COLI
experiment	X-ray (resolution=5.50, R-factor=0.249)
structural superfamily	Sigma2 domain of RNA polymerase sigma factors;Sigma3 and sigma4 domains of RNA polymerase sigma factors;
sequence family	Sigma70, nonessential region; Sigma70 region 3; Sigma70 region 2; Sigma70, region 4; Sigma70 factor, region 12;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4yln_F interface=18,20,21,24,27,32,34,38,267,269,270,304,307,309,312,313,314,316,317,318,321,324,327,332,338,339,341,342,344,345,348,352,387,389,397,400,457,468,469,470,472, aaaqvlssveseigrttDpVRmyMreMgtveLlTregEidiakriedginqvqcsvaeypeaitylleqydrveaeearlsdlitgfvdpnaensidpelarekfaelraqyvvtrdtikakgrshataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveaNlRLvisiakkytnrglqfldliqegniglmkavdkfEyrRgYkfSTYaTWWirQaiTrsIadqaRtiripVHmIEtINklNrisRqmlqemgreptpeelaermlmpedkirkvlkiakEpIsmetpigDdeDshlgdfiedttlelpldsatteslraathdvlagltareakvlrmrfgidmntdytLeevgkqfdvtRERiRqieakalrklrhpsrsevlrsfldd
interface signature	DVRMMLTENRLERYSTYTWWQTIRVHIEINNREIDDLRERR

Estimated binding specificities ?

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# IC=19.158 IC/col=0.661 n_of_columns=29

specificity:

A |  96   5   0  96   0   0  96   0  96   0   5  24  24  96  24  24  24  24  24  24  24  24  24  24   5   0   0  80  66
C |   0   5   0   0   0   0   0   0   0   0  81  24  24   0  24  24  24  24  24  24  24  24  24  24  12   0  96   5  10
G |   0  81  96   0   0   0   0   0   0  96   5  24  24   0  24  24  24  24  24  24  24  24  24  24  69   0   0   5  10
T |   0   5   0   0  96  96   0  96   0   0   5  24  24   0  24  24  24  24  24  24  24  24  24  24  10  96   0   6  10

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updated Sat Aug 2 07:34:24 2025