1a3q_AB : 3D-footprint complex

structure name	HUMAN NF-KAPPA-B P52 BOUND TO DNA
reference	Verdine et al.
source	Homo sapiens
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	1a3q_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1a3q_A interface=16,18,19,21,22,26,179, gpylviveqpkqrgfRfRYgCEgpsHgglpgassekgrktyptvkicnyegpakievdlvthsdpprahahslvgkqcselgicavsvgpkdmtaqfnnlgvlhvtkknmmgtmiqklqrqrlrsrpqglteaeqreleqeakelkkvmdlsivrlrfsaflrslplkpvisqpihdsKspgasnlkisrmdktagsvrggdevyllcdkvqkddievrfyeddengwqafgdfsptdvhkqyaivfrtppyhkmkierpvtvflqlkrkrggdvsdskqftyyp > 1a3q_B interface=16,18,19,21,22,26,179,210, gpylviveqpkqrgfRfRYgCEgpsHgglpgassekgrktyptvkicnyegpakievdlvthsdpprahahslvgkqcselgicavsvgpkdmtaqfnnlgvlhvtkknmmgtmiqklqrqrlrsrpqglteaeqreleqeakelkkvmdlsivrlrfsaflrslplkpvisqpihdsKspgasnlkisrmdktagsvrggdevyllcdKvqkddievrfyeddengwqafgdfsptdvhkqyaivfrtppyhkmkierpvtvflqlkrkrggdvsdskqftyyp
interface signature	RRYCEHK/RRYCEHKK

Estimated binding specificities ?

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# IC=12.041 IC/col=1.095 n_of_columns=11

specificity:

A |   9   0   0   0  67   0   9   0   0   0   0
C |   9   0   0   0   9   0   9  96  96  96  96
G |  69  96  96  96  11   0   9   0   0   0   0
T |   9   0   0   0   9  96  69   0   0   0   0

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updated Tue Jul 29 14:15:25 2025