1a3q_AB : 3D-footprint complex

structure name	HUMAN NF-KAPPA-B P52 BOUND TO DNA
reference	Verdine et al.
source	Homo sapiens
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	p53-like transcription factors;E set domains;
reference complex	1a3q_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1a3q_A interface=16,18,19,21,22,26,179, gpylviveqpkqrgfRfRYgCEgpsHgglpgassekgrktyptvkicnyegpakievdlvthsdpprahahslvgkqcselgicavsvgpkdmtaqfnnlgvlhvtkknmmgtmiqklqrqrlrsrpqglteaeqreleqeakelkkvmdlsivrlrfsaflrslplkpvisqpihdsKspgasnlkisrmdktagsvrggdevyllcdkvqkddievrfyeddengwqafgdfsptdvhkqyaivfrtppyhkmkierpvtvflqlkrkrggdvsdskqftyyp > 1a3q_B interface=16,18,19,21,22,26,179,210, gpylviveqpkqrgfRfRYgCEgpsHgglpgassekgrktyptvkicnyegpakievdlvthsdpprahahslvgkqcselgicavsvgpkdmtaqfnnlgvlhvtkknmmgtmiqklqrqrlrsrpqglteaeqreleqeakelkkvmdlsivrlrfsaflrslplkpvisqpihdsKspgasnlkisrmdktagsvrggdevyllcdKvqkddievrfyeddengwqafgdfsptdvhkqyaivfrtppyhkmkierpvtvflqlkrkrggdvsdskqftyyp
interface signature	RRYCEHK/RRYCEHKK

Estimated binding specificities ?

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# IC=11.623 IC/col=1.057 n_of_columns=11

specificity:

A |   0   0   0   0  75  73   9   0   0   0   7
C |   0   0   0   0   7   7   7  96  96  96  73
G |  96  96  96  96   7   7   7   0   0   0   9
T |   0   0   0   0   7   9  73   0   0   0   7

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updated Mon Sep 9 11:49:19 2024