1dc1_A : 3D-footprint complex

structure name	RESTRICTION ENZYME BSOBI/DNA COMPLEX STRUCTURE: ENCIRCLEMENT OF THE DNA AND HISTIDINE-CATALYZED HYDROLYSIS WITHIN A CANONICAL RESTRICTION ENZYME FOLD (BSOBI RESTRICTION ENDONUCLEASE)
reference	van der Woerd et al.
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=1.70, R-factor=0.190)
structural superfamily	Restriction endonuclease-like;
multimeric complexes	1dc1_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1dc1_A interface=77,127,128,233,235,239,240, kpfenhlksvddlkttyeeyragfiafaleknkrstpyieraralkvaasvaktpkdllylediqdallyasgisdKakkflteddkkesinnlienflepageefidelifryllfqgdslggtmRNiagalaqqkltraiisaldianipykwldsrdkkytnwmdkpeddyeletfakgiswtingkhrtlmynitvslvkknvdiclfncepqqpekylllgelkggiDpAgadEHwktantaltrirnkfsekglspktifigaaiehsmaeeiwdqlqsgsltnsanltkteqvgslcrwiini
interface signature	KRNDAEH

Estimated binding specificities ?

readout + contact

# IC=3.437 IC/col=0.859 n_of_columns=4

specificity:

A |   0  10  58   0
C |  95   8   2   0
G |   1  64  32  95
T |   0  14   4   1

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: BSOBI
CTCGAG	PubMed	1dc1_A(1.01e-06), 1dc1_AB(1.24e-09)
CCCGGG	PubMed	1dc1_A(1.30e-02), 1dc1_AB(1.24e-02)

Dendrogram of similar interfaces ?

matrix format

  
  KG--------RCNG----DGAG------ECHG--   L       +---------------------1dc1_A    
                                           +---2 
  ----KG----------SG----RGSADCRG----   L   !   +---------------------3dvo_D    
                                         --3 
  --RG--QGFCACKG----RGKGECVC------RT   L   !    +--------------------6eko_A    
                                           +----1 
  ------QG--VCRCKG------------------   L        +--------------------5dwa_A

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updated Fri Sep 13 15:30:19 2024