1efa_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF
reference	Bell et al.
source	Escherichia coli
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	Periplasmic binding protein-like I;lambda repressor-like DNA-binding domains;
reference complex	1efa_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1efa_A interface=5,6,15,16,17,20,21,52,55,56, kpvtLYdvaeyagvSYQtvSRvvnqashvsaktrekveaamaelnyipnrvAqqLAgkqslligvatsslalhapsqivaaiksradqlgasvvvsmversgveacktavhnllaqrvsgliinyplddqdaiaveaactnvpalfldvsdqtpinsiifshedgtrlgvehlvalghqqiallagplssvsarlrlagwhkyltrnqiqpiaeregdwsamsgfqqtmqmlnegivptamlvandqmalgamraitesglrvgadisvvgyddtedsscyipplttikqdfrllgqtsvdrllqlsqgqavkgnqllpvslvkrktt > 1efa_B interface=5,6,15,16,17,20,21,28,52,55,56, kpvtLYdvaeyagvSYQtvSRvvnqasHvsaktrekveaamaelnyipnrvAqqLAgkqslligvatsslalhapsqivaaiksradqlgasvvvsmversgveacktavhnllaqrvsgliinyplddqdaiaveaactnvpalfldvsdqtpinsiifshedgtrlgvehlvalghqqiallagplssvsarlrlagwhkyltrnqiqpiaeregdwsamsgfqqtmqmlnegivptamlvandqmalgamraitesglrvgadisvvgyddtedsscyipplttikqdfrllgqtsvdrllqlsqgqavkgnqllpvslvkrkttla
interface signature	LYSYQSRALA/LYSYQSRHALA

Estimated binding specificities ?

readout + contact

# IC=16.294 IC/col=1.086 n_of_columns=15

specificity:

A |   4   0   0   0   0  87   4   0   0   0   4   0  96   0  86
C |   4   0   0  18   0   0   4  96   0  91   6  86   0  96   2
G |   9   0  96   0  91   0  77   0  96   1   4   0   0   0   4
T |  79  96   0  78   5   9  11   0   0   4  82  10   0   0   4

scan!

home
updated Tue Jul 29 14:33:52 2025