interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF C-REL BOUND TO DNA
(C-REL PROTO-ONCOGENE PROTEIN)
referenceRuetsche et al. Structure 9 669 2001
sourceGallus gallus
experimentX-ray (resolution=2.85, R-factor=?)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1gji_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRYCER

Estimated binding specificities ?

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# IC=4.319 IC/col=0.864 n_of_columns=5 specificity:   
A |  15   0   0  96  54
C |  13   0   0   0  13
G |  27  96  96   0  13
T |  41   0   0   0  16
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: C-REL
TTGGAAATTCCPubMed1gji_A(7.38e-03), 1gji_AB(1.89e-04)
GGGAAAGTACPubMed1gji_A(5.42e-03)
CGGAGTTTCCPubMed1gji_A(5.42e-03), 1gji_AB(1.02e-04)

Dendrogram of similar interfaces ?

matrix format
  
  RGRGYTCTEC--------RT------   L                               +1gji_A    
                                                         +-----1 
  RGRG----EC--------RGPTKT--   L                         !     +2ram_A    
                                                         ! 
  RGRGYTCCEC----KT--KTPTKTRG   L          +--------------6     +1nfk_A    
                                          !              !   +-2 
  RCRCYC--EC--HC----KT----RG   L          !              !   ! +1svc_P    
                                          !              +---5 
  RGRGYA--EC--HG----KG------   L   +------7                  ! +7w7l_B    
                                   !      !                  +-3 
  RGRGYTCCEC--HG----KG------   L   !      !                    +1a3q_A    
                                 --8      ! 
  RG--YT--TTECRG------QA----   L   !      +--------------------1imh_C    
                                   ! 
  ----------------RTVC------   L   !                          +4l0y_A    
                                   +--------------------------4 
  ----------------RTVC------   L                              +3wu1_A    
                                 

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updated Fri Sep 13 15:37:48 2024