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structure nameSOLUTION STRUCTURE OF THE DNA COMPLEX OF HUMAN TRF1
(TELOMERIC REPEAT BINDING FACTOR 1)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHomeodomain-like;
sequence familyMyblike DNAbinding domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSVMKDRT

Estimated binding specificities ?

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# IC=4.906 IC/col=0.818 n_of_columns=6 specificity:   
A |   0   0  32   6  13  51
C |   7   0   0   8   0  14
G |  89  96  64   6   0  12
T |   0   0   0  76  83  19
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RA------------------ITQTNAMG--   L                                           +5zjt_E    
                                                                +--------------2 
  RT------------------NT--NAITRG   L                     +------9              +5zjt_B    
                                                         !      ! 
  RA----------------KGSAQA------   L                     !      +--------------6j5b_C    
                                                         !  
  RT----------------KTIAQCNA----   L                     !                    +1ig7_A    
                                                         !                  +-5 
  RT------------------ITQCNAACRG   L                     !                  ! +6a8r_A    
                                                      +-11           +------7 
  --------------------IA--NA----                      !  !           !      !  +4qtr_D    
                                                      !  !           !      +--3 
  RT------------------NT--NAIARG   L                  !  !    +------8         +1b72_B    
                                                      !  !    !      ! 
  RT------------------NT--NA--RG   L                  !  !    !      !        +1b8i_B    
                                                      !  !    !      +--------4 
  --------------------NCITNARGRG   L               +-12  +---10               +6fqq_E    
                                                   !  !       !  
  RT------------------IAKGNA----   L               !  !       !                +2hdd_A    
                                                   !  !       !              +-1 
  --------------RTQT--ITQANAVTKT   L               !  !       +--------------6 +2ld5_A    
                                                +-13  !                      ! 
  RT----------STVC--KGDCRG------   L            !  !  !                      +-1w0t_A    
                                                !  !  !  
  ------------YTVC--KGDCKC------   L         +-14  !  +-----------------------2qhb_A    
                                             !  !  !  
  RA----YA------------IAQCNAYCKG   L         !  !  +-------------------------5flv_I    
                                          +-15  !  
  --------------KG--RTEC--------   L      !  !  +---------------------------1h89_C    
                                       +-16  !  
  ----------YC------------------   L   !  !  +-----------------------------2yvh_A    
                                     -17  !  
  --------LT--RTSGTGQTRG--------   L   !  +-----------------------------2xro_E    
                                       !  
  --RGRT------------------------   L   +-----------------------------6lui_A    
                                     

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updated Thu Sep 12 14:45:28 2024