1kb2_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF VDR DNA-BINDING DOMAIN BOUND TO MOUSE OSTEOPONTIN (SPP) RESPONSE ELEMENT
reference	Shaffer et al. 'EMBO 21 2242 2002
source	Homo sapiens
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1kb2_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1kb2_A interface=21,24,28,29,82, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrKremilkr > 1kb2_B interface=21,24,28,29, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrkrem
interface signature	EKRRK/EKRR

Estimated binding specificities ?

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# IC=8.833 IC/col=0.631 n_of_columns=14

specificity:

A |   0   0   1  13  78  24  24  24  23   0   0   0  24  65
C |   0   0  31  74   5  24  24  24   7   0  14   0  24  11
G |  96   0   1   4   8  24  24  24  61  96   0  92  24  11
T |   0  96  63   5   5  24  24  24   5   0  82   4  24   9

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updated Sun Jan 4 21:33:01 2026