1kb2_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF VDR DNA-BINDING DOMAIN BOUND TO MOUSE OSTEOPONTIN (SPP) RESPONSE ELEMENT
reference	Shaffer et al. 'EMBO 21 2242 2002
source	Homo sapiens
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1kb2_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1kb2_A interface=21,24,28,29,82, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrKremilkr > 1kb2_B interface=21,24,28,29, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrkrem
interface signature	EKRRK/EKRR

Estimated binding specificities ?

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# IC=9.063 IC/col=0.647 n_of_columns=14

specificity:

A |   8  24   2  83   0   2  24  24  24   3   2  50  93   0
C |   8  24  93   0  96  78  24  24  24   6   2   6   3  96
G |   6  24   0  13   0   3  24  24  24   2  34  32   0   0
T |  74  24   1   0   0  13  24  24  24  85  58   8   0   0

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updated Mon Sep 9 12:34:22 2024