1kb2_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF VDR DNA-BINDING DOMAIN BOUND TO MOUSE OSTEOPONTIN (SPP) RESPONSE ELEMENT
reference	Shaffer et al. 'EMBO 21 2242 2002
source	Homo sapiens
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1kb2_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1kb2_A interface=21,24,28,29,82, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrKremilkr > 1kb2_B interface=21,24,28,29, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrkrem
interface signature	EKRRK/EKRR

Estimated binding specificities ?

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# IC=8.770 IC/col=0.626 n_of_columns=14

specificity:

A |   7  24   0  73   0   7  24  24  24   9   5  56  96   0
C |   9  24  96   0  96  62  24  24  24   7   0   4   0  96
G |  12  24   0  23   0   3  24  24  24   0  27  27   0   0
T |  68  24   0   0   0  24  24  24  24  80  64   9   0   0

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updated Wed Jun 24 09:37:16 2026