1kb4_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF VDR DNA-BINDING DOMAIN BOUND TO A CANONICAL DIRECT REPEAT WITH THREE BASE PAIR SPACER (DR3) RESPONSE ELEMENT
reference	Shaffer et al. 'EMBO 21 2242 2002
source	Homo sapiens
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1kb2_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1kb4_A interface=21,24,28,29,82, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrKremilkrkeee > 1kb4_B interface=21,24,28,29, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrkremilkrkeeealkdsl
interface signature	EKRRK/EKRR

Estimated binding specificities ?

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# IC=8.876 IC/col=0.634 n_of_columns=14

specificity:

A |   0   0  24   7  81  24  24  24  29   0   0  24   0  66
C |   0   0  24  75   8  24  24  24   7   0   0  24  96   7
G |  96  96  24   0   0  24  24  24  51  96  96  24   0   9
T |   0   0  24  14   7  24  24  24   9   0   0  24   0  14

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updated Mon Sep 9 12:34:29 2024