1kb4_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF VDR DNA-BINDING DOMAIN BOUND TO A CANONICAL DIRECT REPEAT WITH THREE BASE PAIR SPACER (DR3) RESPONSE ELEMENT
reference	Shaffer et al. 'EMBO 21 2242 2002
source	Homo sapiens
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1kb2_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1kb4_A interface=21,24,28,29,82, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrKremilkrkeee > 1kb4_B interface=21,24,28,29, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrkremilkrkeeealkdsl
interface signature	EKRRK/EKRR

Estimated binding specificities ?

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# IC=7.825 IC/col=0.602 n_of_columns=13

specificity:

A |   0  24   0   0   0  24  24  24   9  11  24   0   0
C |   0  24  96  96  67  24  24  24   9   9  24  96  96
G |  96  24   0   0   9  24  24  24  19  57  24   0   0
T |   0  24   0   0  20  24  24  24  59  19  24   0   0

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updated Tue Jul 29 15:03:12 2025