1kb4_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF VDR DNA-BINDING DOMAIN BOUND TO A CANONICAL DIRECT REPEAT WITH THREE BASE PAIR SPACER (DR3) RESPONSE ELEMENT
reference	Shaffer et al. 'EMBO 21 2242 2002
source	Homo sapiens
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1kb2_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1kb4_A interface=21,24,28,29,82, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrKremilkrkeee > 1kb4_B interface=21,24,28,29, ricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrkremilkrkeeealkdsl
interface signature	EKRRK/EKRR

Estimated binding specificities ?

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# IC=7.817 IC/col=0.601 n_of_columns=13

specificity:

A |   0   0  24  19  59  24  24  24  19   0   0  24   0
C |   0   0  24  57  19  24  24  24  10   0   0  24  96
G |  96  96  24   9   9  24  24  24  67  96  96  24   0
T |   0   0  24  11   9  24  24  24   0   0   0  24   0

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updated Sun Jan 4 21:33:10 2026