1kb6_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF VDR DNA-BINDING DOMAIN BOUND TO RAT OSTEOCALCIN (OC) RESPONSE ELEMENT
reference	Shaffer et al. 'EMBO 21 2242 2002
source	Homo sapiens
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1kb2_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1kb6_A interface=22,25,29,30,83, pricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrKremilkrkeee > 1kb6_B interface=22,25,29,30, pricgvcgdratgfhfnamtcEgcKgffRRsmkrkalftcpfngdcritkdnrrhcqacrlkrcvdigmmkefiltdeevqrkremilkrkeeealkdslr
interface signature	EKRRK/EKRR

Estimated binding specificities ?

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# IC=8.887 IC/col=0.592 n_of_columns=15

specificity:

A |  16   0  24   0   0   5  24  24  24  13  24  46   0   0   0
C |  10   0  24  96  96  40  24  24  24   8  24  32  96  96  87
G |  10  96  24   0   0   8  24  24  24  10  24   8   0   0   2
T |  60   0  24   0   0  43  24  24  24  65  24  10   0   0   7

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updated Tue Jul 29 15:03:23 2025