interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF E. COLI SEQA COMPLEXED WITH HEMIMETHYLATED DNA
(SeqA protein)
referenceGuirlando et al. NAT.STRUCT.BIOL. 9 839 2002
sourceEscherichia coli
experimentX-ray (resolution=2.65, R-factor=?)
structural superfamilyReplication modulator SeqA, C-terminal DNA-binding domain;
sequence familySeqA protein;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRQNNR

Estimated binding specificities ?

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# IC=2.714 IC/col=0.452 n_of_columns=6 specificity:   
A |   9  24   0  24   9   9
C |   9  24   0  24   9   9
G |  69  24   0  24  67  69
T |   9  24  96  24  11   9
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updated Sat Jan 10 04:47:31 2026