1n5y_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO POST-TRANSLOCATION AZTMP- TERMINATED DNA (COMPLEX P)
reference	Sarafianos et al. 'Embo 21 6614 2002
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1n5y_A interface=94,183,184,356,448, pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsagirk > 1n5y_B interface= pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql
interface signature	IYMRR/IYMR

Estimated binding specificities ?

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# IC=2.298 IC/col=0.135 n_of_columns=17

specificity:

A |   7   7  24  24  24  24  24  24  24  24  24  24  24  24  24  73   7
C |   7   7  24  24  24  24  24  24  24  24  24  24  24  24  24   2  73
G |  73  73  24  24  24  24  24  24  24  24  24  24  24  24  24  14   7
T |   9   9  24  24  24  24  24  24  24  24  24  24  24  24  24   7   9

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updated Sun Jan 4 22:09:58 2026