structure name | CRYSTAL STRUCTURE OF MYC-MAX RECOGNIZING DNA (MYC PROTO-ONCOGENE PROTEIN) |
reference | Burley et al. 'Cell(Cambridge,Mass.)' 112 193 2003 |
source | HOMO SAPIENS |
experiment | X-ray (resolution=1.80, R-factor=0.219) |
structural superfamily | HLH, helix-loop-helix DNA-binding domain; |
sequence family | Helixloophelix DNAbinding domain; Myc leucine zipper domain; |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | KHNERR |
Estimated binding specificities ?
contact |
A | 13 0 16 0 C | 54 0 13 0 G | 16 96 13 96 T | 13 0 54 0scan! |
Related DNA sequences reported in the literature ?
site | source | matches (E-value) |
---|---|---|
term: MYC | ||
CACGTG | PubMed | 1nkp_A(4.51e-04), 1nkp_AB(8.79e-10), 1nkp_DE(1.19e-09) |
CATGTG | PubMed | 1nkp_AB(3.45e-05), 1nkp_DE(8.58e-05) |
CACGTGT | PubMed | 1nkp_A(1.25e-03), 1nkp_AB(2.57e-08), 1nkp_DE(3.33e-08) |
CACCACGTGGTG | PubMed | 1nkp_A(8.54e-03), 1nkp_AB(4.28e-06), 1nkp_DE(5.25e-06) |
AACGTT | PubMed | 1nkp_AB(3.47e-03), 1nkp_DE(4.01e-03) |
AACGTG | PubMed | 1nkp_A(4.51e-04), 1nkp_AB(6.52e-06), 1nkp_DE(8.14e-06) |
CANNTG | PubMed | 1nkp_AB(3.37e-03), 1nkp_DE(4.01e-03) |
GGCCACGTG | PubMed | 1nkp_A(3.55e-03), 1nkp_AB(5.43e-07), 1nkp_DE(6.80e-07) |
CAACGTG | PubMed | 1nkp_A(1.25e-03), 1nkp_AB(5.35e-05), 1nkp_DE(6.46e-05) |
Dendrogram of similar interfaces ?
matrix formatKT----HGNT----ECRCRG L +1nkp_A +-1 ------HGNT--LGECRCRC L +----3 +5i50_B ! ! ------HGNT--MTEARCRG L +---------5 +-1nlw_D ! ! ------HGNT----ECRCRG L +-6 +------7d8t_A ! ! ------HGNT----ECRCRG L ! ! +-1nkp_E +------8 +--------------4 ------HG------ETRCRG L ! ! +-5gnj_I +-9 ! --NTRGEC----RC------ ! ! +-----------------2ql2_A ! ! ----------NG--SCHTRC -10 +------------------------5nj8_C ! ------HGNT--ITECYCRC L ! +-----------------7f2f_B +-------7 ------HGST--ITETRCRG L ! +4h10_A +----------------2 ------HG------ETRTRG L +5v0l_A |
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updated Thu Sep 12 15:02:22 2024