1pvp_AB : 3D-footprint complex

structure name	BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7
reference	Baldwin et al.
source	Escherichia phage P1
experiment	X-ray (resolution=2.35, R-factor=?)
structural superfamily	DNA breaking-rejoining enzymes;lambda integrase-like, N-terminal domain;
reference complex	7rhx_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1pvp_A interface= tsdevrknlmdmfrdrqafsehtwkmllsvcrswaawcklnnrkwfpaepedvrdyllylqarglavktiqqhlgqlnmlhrrsglprpsdsnavslvmrrirkenvdagerakqalafertdfdqvrslmensdrcqdirnlaflgiayntllraaeiarirvkdisrtdggrmlihigrtktlvstagvekalslgvtklverwisvsgvaddpnnylfcrvrkngvaapsatsqlslsalhgifgathrliygakddsgqrylawsghsarvgaardmaragvsipeimqaggwtnvnivmnyirnldsetgamvrlled > 1pvp_B interface=22,23,25,26,29,68,69,72,76,183,223,225,226,239,241,244,264,299, tsdevrknlmdmfrdrqafseHTwKMllSvcrswaawcklnnrkwfpaepedvrdyllylqarglavKTiqQhlgQlnmlhrrsglprpsdsnavslvmrrirkenvdagerakqalafertdfdqvrslmensdrcqdirnlaflgiayntllraaeiarirvkdisrtdggrmlihigrtKtlvstagvekalslgvtklverwisvsgvaddpnnylfcRvRKngvaapsatsqlSlSalHgifgathrliygakddsgqRylawsghsarvgaardmaragvsipeimqaggwtNvnivmnyirtgamvrlled
interface signature	/HTKMSKTQQKRRKSSHRN

Estimated binding specificities ?

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# IC=9.942 IC/col=0.765 n_of_columns=13

specificity:

A |   0   0  96   0  96   6  24   6  60  24  24   0  78
C |   6  12   0   0   0  12  24   0  12  24  24   0   6
G |   0   0   0   0   0  12  24  90  12  24  24   0   6
T |  90  84   0  96   0  66  24   0  12  24  24  96   6

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updated Sun Jan 4 23:16:19 2026