1r0a_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE COVALENTLY TETHERED TO DNA TEMPLATE-PRIMER SOLVED TO 2.8 ANGSTROMS
reference	Arnold et al. J.Virol. 78 3387 2004
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1r0a_A interface=94,115,157,183,184,356,358,448, pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmRgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsagirk > 1r0a_B interface= pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmRgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql
interface signature	IYPYMRRR/IYPYMRR

Estimated binding specificities ?

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# IC=5.035 IC/col=0.296 n_of_columns=17

specificity:

A |   0   8  24  24  24  24  24  24   9  96  24  24  24  24  24   9  73
C |  96   7  24  24  24  24  24  24   7   0  24  24  24  24  24   7   7
G |   0  81  24  24  24  24  24  24  73   0  24  24  24  24  24  66   9
T |   0   0  24  24  24  24  24  24   7   0  24  24  24  24  24  14   7

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updated Sun Jan 4 23:20:06 2026