1rtd_AB : 3D-footprint complex

structure name	STRUCTURE OF A CATALYTIC COMPLEX OF HIV-1 REVERSE TRANSCRIPTASE: IMPLICATIONS FOR NUCLEOSIDE ANALOG DRUG RESISTANCE
reference	Harrison et al. Science 282 1669 1998
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1rtd_A interface=61,74,94,115,157,183,184,258,448,475, kispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiCklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltdttnQktqlqaiylalqdsglevnivtdsqyalgiiqaqpdeseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 1rtd_B interface= spietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaIkkkdstkwrklvDfrelnkrtqdfwevqlgipHpaglkkkksvtvldvgdayfSvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaIfqssmtkilepfrkqnpdiviyqymDDlyvgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypGikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql
interface signature	FLIYPYMCRQ/IDHSIDDG

Estimated binding specificities ?

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# IC=6.380 IC/col=0.354 n_of_columns=18

specificity:

A |   8   0  24   7  24  24  24  24  24  24  24  24  24  24   7   0   0   7
C |   7  96  24  66  24  24  24  24  24  24  24  24  24  24  73  96   0   9
G |   0   0  24   7  24  24  24  24  24  24  24  24  24  24   7   0  96  73
T |  81   0  24  16  24  24  24  24  24  24  24  24  24  24   9   0   0   7

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updated Sun Jan 4 23:26:44 2026