interface graph thumbnail
legend  pdf

structure nameTAQ POLYMERASE (E.C.2.7.7.7)/DNA/B-OCTYLGLUCOSIDE COMPLEX
(PROTEIN TAQ POLYMERASE)
referenceSteitz et al.
sourceThermus aquaticus
experimentX-ray (resolution=3.00, R-factor=?)
structural superfamilyDNA/RNA polymerases;PIN domain-like;5' to 3' exonuclease, C-terminal subdomain;Ribonuclease H-like;
sequence familyDNA polymerase family A; Taq polymerase, exonuclease; 5'3' exonuclease, Nterminal resolvase; 5'3' exonuclease, Cterminal SAM fold;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNNFYRRNQ

Estimated binding specificities ?

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# IC=2.170 IC/col=0.542 n_of_columns=4 specificity:   
A |   9  12  19   0
C |   9  60  19  96
G |   9  12  39   0
T |  69  12  19   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----------------------------------NANC------FC--YG------RG--------------RGNGQC--   L                    +------------1tau_A    
                                                                                                          ! 
  --------------VAAAKC------------RTNGNC----TC----YCMCSAHARAQAEA------------NGQG--                        !            +-6fbc_A    
                                                                                                          !          +-3 
  ------------------RC------------RANGNGRT----YG--YT--SCYC------------------NTQT--   L                    !          ! +-6vdd_A    
                                                                                                        +-7        +-4 
  ------------------KT----YG------RGNGNGRC----YG--YAIGSCYC----NGRC--FG--------QAHG                      ! !        ! ! +-4yfu_D    
                                                                                                        ! !        ! +-2 
  LCNGKGYGMGRCEG------------SGHGVC------------------------------------------------                      ! !      +-5   +-1kln_A    
                                                                                                        ! !      ! ! 
  --------------------KA--------------NT--------------------------------------QGHT   L     +------------8 !      ! !  +-6xbu_A    
                                                                                           !            ! +------6 +--1 
  ------------------NA--KG--------RC--NT----QC--------------------NG--YGATRT--QGHC   L     !            !        !    +-4x0p_B    
                                                                                           !            !        ! 
  ------------------KT------------RG------EGKGYGACYCAC----RC----------QTATRTNGQGHC   L   +-9            !        +-----4xvk_A    
                                                                                         ! !            ! 
  ----------------------KT--------RTNG------------YA--------------------------QA--       ! !            +--------------1x9m_A    
                                                                                       -10 ! 
  ----------------------NG--------RTTT------IGYG--YG------------------------NGQT--       ! +---------------------------4ztu_A    
                                                                                         !  
  ----------------------------------------------TGYGVG--YT------------------------   L   +----------------------------4boc_A    
                                                                                       

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updated Fri Sep 13 16:00:54 2024