1x9n_A : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

Dendrogram of similar interfaces ?

matrix format

structure name	CRYSTAL STRUCTURE OF HUMAN DNA LIGASE I BOUND TO 5'-ADENYLATED, NICKED DNA (DNA ligase I)
reference	Tomkinson et al. Nature 432 473 2004
source	Homo sapiens
experiment	X-ray (resolution=3.00, R-factor=0.236)
structural superfamily	ATP-dependent DNA ligase DNA-binding domain;DNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;
sequence family	ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal re;
reference complex	6p0c_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1x9n_A interface=44,501,529,603, dpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsaRlrmvetlsnllrsvvalsppdllpvlylslnhlgppqqglelgvgdgvllkavaqatgrqlesvraeaaekgdvglvaemlppppltasgvfskfrdiarltgsastakkidiikglfvacrhsearfiarslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeqgmilkqtfcevpdldriipvllehglerlpehcklspgiplkpmlahptrgisevlkrfeeaaftceykydgqraqihaleggevkifsrnqedntgkypdiisripkiklpsvtsfildteavawdrekkqiqpfqvlttrkrkevdaseiqvqvclyafdliylngeslvreplsrrrqllrenfvetegefvfatsldtkdieqiaefleqsvkdsceglmvktldvdatyeiakrshnwlklkkdyldgvgdtldlvvigaylgrgKragryggfllasydedseelqaicklgTgfsdeeleehhqslkalvlpsprpyvridgavipdhwldpsavwevkcadlslspiypaarglvdsdkgislrFprfirvredkqpeqattsaqvaclyrkqs

  
  RT------------------------KG--TT--FG--   L                        +------1x9n_A    
                                                              +-----3 
  ------------------------------ST--FG--                      !     ! +----6bkg_A    
                                                              !     +-1 
  YC--------------FT--------------RCFG--               +------4       +----3l2p_A    
                                                       !      ! 
  --------------------------------FGLGIT               !      !      +-----6dt1_A    
                                                    +--5      +------2 
  ------------------MG----------SA--FC--            !  !             +-----6rar_I    
                                               +----6  ! 
  --------------------NC------KG----QT--       !    !  +-------------------6iml_A    
                                             --7    ! 
  --------------FG------LC--KG--TA--FC--       !    +----------------------6gdr_A    
                                               ! 
  --YALARAKAIAEA----------FA------------       +---------------------------2hvr_B

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updated Mon Dec 18 06:15:52 2023