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structure nameTHE GCN4 BASIC REGION LEUCINE ZIPPER BINDS DNA AS A DIMER OF UNINTERRUPTED ALPHA HELICES: CRYSTAL STRUCTURE OF THE PROTEIN-DNA COMPLEX
referenceEllenberger et al.
sourceSACCHAROMYCES CEREVISIAE
experimentX-ray (resolution=2.90, R-factor=?)
structural superfamilyLeucine zipper domain;
reference complex2dgc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKNTAAR/KNTAASR

Estimated binding specificities ?

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# IC=3.551 IC/col=0.444 n_of_columns=8 specificity:   
A |  31  12  14  75   3   8  13  72
C |  13  12  11   8   4   7  54   7
G |  14  12  60   6  85   7  14   9
T |  38  60  11   7   4  74  15   8
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updated Wed Jun 24 12:08:20 2026