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legend  pdf

structure nameX-RAY DATA DO NOT SUPPORT HOOGSTEEN BASE-PAIRING DURING REPLICATION BY HUMAN POLYMERASE IOTA
(Polymerase DNA directed iota)
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.261)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
multimeric complexes1t3n_AB
reference complex3q8p_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYQLVLERRSQ

Estimated binding specificities ?

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# IC=2.027 IC/col=0.405 n_of_columns=5 specificity:   
A |   0  12  24  12  18
C |   0  12  24  60  42
G |  96  60  24  12  18
T |   0  12  24  12  18
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updated Sun Jun 28 05:15:14 2026