Estimated binding specificities ?

structure nameCRYSTAL STRUCTURE OF KH1 DOMAIN OF HUMAN POLY(C)-BINDING PROTEIN-2 WITH C-RICH STRAND OF HUMAN TELOMERIC DNA
(PolyrC-binding protein 2)
referenceStroud et al. J.Biol.Chem. 280 38823 2005
sourceHomo sapiens
experimentX-ray (resolution=1.70, R-factor=0.215)
structural superfamilyEukaryotic type KH-domain KH-domain type I;
sequence familyKH domain;
multimeric complexes2axy_AC 2pqu_AC
redundant complexes2pqu_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
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# IC=6.387 IC/col=1.277 n_of_columns=5 specificity:   
A |  96   0   0   0   2
C |   0  96  96  96   2
G |   0   0   0   0   2
T |   0   0   0   0  90
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --TTRT----SAICKAVCRC----NTICECNCRC------------   L                         +2axy_C    
                                                                           +-1 
  --------VCSCICKCVCRC------ICECNCRCPANAFAKC--KC       +-------------------2 +3vke_A    
                                                       !                   ! 
  ------RTVTITIT--IT--QTFT--------RT------------   L --4                   +--1j4w_A    
                                                       ! 
  RG--------------------------------RC----------   L   !         +------------2itl_B    
                                                       +---------3 
  ----TA----------------------------------RTKC--   L             +------------4er8_A

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updated Mon Jun 29 14:56:32 2026