2e1c_A : 3D-footprint complex

structure name	STRUCTURE OF PUTATIVE HTH-TYPE TRANSCRIPTIONAL REGULATOR PH1519/DNA COMPLEX (Putative HTH-type transcriptional regulator PH1519)
reference	Suzuki et al. Structure 15 1542 2007
source	Pyrococcus horikoshii
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	Dimeric alpha+beta barrel;"Winged helix" DNA-binding domain;Dimeric alpha+beta barrel;Dimeric alpha+beta barrel;
sequence family	AsnC family;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2e1c_A interface=21,31,32,33,34,36, pldeidkkiikilqndgkapLreiskitglAESTiHerirklresgvikkftaiidpealgysmlafilvkvkagkysevasnlakypeivevyettgdydmvvkirtknseelnnfldligsipgvegthtmivlkthkettelpi
interface signature	LAESTH

Estimated binding specificities ?

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# IC=4.007 IC/col=0.801 n_of_columns=5

specificity:

A |   0   0  69  67  67
C |   0   0   9  11  11
G |   0  96   9   9   9
T |  96   0   9   9   9

scan!

Dendrogram of similar interfaces ?

matrix format

  
  LTAGETSGTTHT--------------------------   L           +-----------------2e1c_A    
                                               +-------2 
  --------------TAFCSG--------LATGSGVGFA   L   !       !        +--------5tkz_B    
                                             --3       +--------1 
  --------------------KTTGYCNG----------   L   !                +--------1b3t_A    
                                               ! 
  ------------YG------------------------       +-------------------------2heo_D

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updated Sun Aug 3 06:11:01 2025