2gb7_A : 3D-footprint complex

structure name	METAL-DEPLETED ECL18KI IN COMPLEX WITH UNCLEAVED, MODIFIED DNA (R.ECL18KI)
reference	Szczepanowski et al.
source	ENTEROBACTER CLOACAE
experiment	X-ray (resolution=1.70, R-factor=0.208)
structural superfamily	Restriction endonuclease-like;
sequence family	EcoRII C terminal;
multimeric complexes	2fqz_AB 2fqz_CD 2gb7_AB 2gb7_CD
redundant complexes	2fqz_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2gb7_A interface=112,115,116,175,177,178,179, rlspgefktliskerkshfitpfalvyktfcdlgydqknsdyflnnpseyiiamrkncwkefepfekefttrmlsylideerikdmspydairdftmeypthiydlalsntQsrRSragkefesilellmmgagipvdvqgainqigklvdlvmpgvvqytsnkrntmlisaktTlRERwqevpeevnrtgiremylatlddsfseetinilyeanvvvvttvenknfkyknnnrvltfedmlqsamelsrkwnnvsytdsekeeiqqsilkqiekysdfpyvvnyyrnrlsa
interface signature	QRSTRER

Estimated binding specificities ?

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# IC=4.942 IC/col=0.988 n_of_columns=5

specificity:

A |   0   0   0   4  11
C |  96  96   0   3  56
G |   0   0  96  77  12
T |   0   0   0  12  17

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: ECL18KI
CCGGC	PubMed	2gb7_A(3.63e-08), 2fqz_AB(3.54e-04), 2fqz_CD(3.54e-04), ... (total=6)
GCCGGC	PubMed	2gb7_A(1.67e-07), 2fqz_AB(1.12e-03), 2fqz_CD(1.12e-03), ... (total=6)

Dendrogram of similar interfaces ?

matrix format

  
  RA--CAWA----QG--RCSG--AAEATGRGECRG----   L                  +-------------2gb7_A    
                                                 +------------1 
  --RA--EAYAFA--RAKCSCRAAASA--KGDGRG----   L   +-2            +-------------3hqg_A    
                                               ! ! 
  --------------------------------ET----     --3 +--------------------------6g3b_A    
                                               ! 
  ----------------EAKT--------NA--KGDCKA   L   +---------------------------3wvk_C

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updated Fri Sep 13 16:18:02 2024