2gzk_A : 3D-footprint complex

structure name	STRUCTURE OF A COMPLEX OF TANDEM HMG BOXES AND DNA (SEX-DETERMINING REGION ON Y HMGB1)
source	HOMO SAPIENS, RATTUS RATTUS
experiment	NMR
structural superfamily	HMG-box;
sequence family	HMG high mobility group box;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2gzk_A interface=7,10,12,13,20,32,36,74,76,78,81,91,96,97,100,116,120, vqdrvkRpmNaFIvwsrdqRrkmalenprmrNseiSkqlgyqwkmlteaekwpffqeaqklqamhrekypnykYrKgEtkKkfkdpnapkRppsaFFlfCseyrpkikgehpglsIgdvAkklgemwnntaaddkqpyekkaaklkekyekdiaayrak
interface signature	RNFIRNSYKEKRFFCIA

Estimated binding specificities ?

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# IC=13.481 IC/col=0.843 n_of_columns=16

specificity:

A |   0   0  19   0   0   0   2   0  24  24   0  67   0   0  24   9
C |   0  96   4   0   0   0   9   0  24  24  11   4   0  96  24  72
G |  96   0  57   0   0  96   4   0  24  24  76  11   0   0  24   6
T |   0   0  16  96  96   0  81  96  24  24   9  14  96   0  24   9

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: HMG
AACAAAG	PubMed	2gzk_A(2.32e-04)
AACAAT	PubMed	2gzk_A(3.69e-04)
ATTGTT	PubMed	2gzk_A(3.69e-04)
GAACAAT	PubMed	2gzk_A(3.88e-03)

Dendrogram of similar interfaces ?

matrix format

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updated Sun Aug 3 06:14:04 2025