interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF ESCHERICHIA COLI SIGMAE REGION 4 BOUND TO ITS-35 ELEMENT DNA
(RNA polymerase Sigma E factor)
referenceDarst et al. 'Plos 4 e269 2006
sourceEscherichia coli K12
experimentX-ray (resolution=2.30, R-factor=0.241)
structural superfamilySigma3 and sigma4 domains of RNA polymerase sigma factors;
sequence familySigma70, region 4;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYTRSFR

Estimated binding specificities ?

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# IC=6.778 IC/col=0.968 n_of_columns=7 specificity:   
A |  12   0  12   0   0   0   0
C |  12   0  24   0  96  96  12
G |  60  96  12   0   0   0  84
T |  12   0  48  96   0   0   0
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Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: SIGMAE
GGAACTTPubMed2h27_A(6.96e-05)

Dendrogram of similar interfaces ?

matrix format



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updated Sun Aug  3 06:14:20 2025