2hof_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE PRE-CLEAVAGE SYNAPTIC COMPLEX IN THE CRE- LOXP SITE-SPECIFIC RECOMBINATION
reference	Van Duyne et al. J.Biol.Chem. 282 24004 2007
source	Enterobacteria phage P1
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	DNA breaking-rejoining enzymes;lambda integrase-like, N-terminal domain;
reference complex	7rhx_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2hof_A interface=21,22,24,25,28,67,68,71,75,209,211,212,225,227,230,250,288, sdevrknlmdmfrdrqafseHTwKMllSvcrswaawcklnnrkwfpaepedvrdyllylqarglavKTiqQhlgQlnmlhrrsglprpsdsnavslvmrrirkenvdagerakqalafertdfdqvrslmensdrcqdirnlaflgiayntllriaeiarirvkdisrtdggrmlihikalslgvtklverwisvsgvaddpnnylfcRvRKngvaapsatsqlStRalEgifeathrliygakddsgqRylawsghsarvgaardmaragvsipeimqaggwtnvnIvmnyirnldsetgamvrlled > 2hof_B interface=21,22,24,25,28,67,68,70,71,75,222,224,225,238,240,243,263,298, sdevrknlmdmfrdrqafseHTwKMllSvcrswaawcklnnrkwfpaepedvrdyllylqarglavKTiQQhlgQlnmlhrrsglprpsdsnavslvmrrirkenvdagerakqalafertdfdqvrslmensdrcqdirnlaflgiayntllriaeiarirvkdisrtdggrmlihigrtatlvstagvekalslgvtklverwisvsgvaddpnnylfcRvRKngvaapsatsqlStRalEgifeathrliygakddsgqRylawsghsarvgaardmaragvsipeimqaggwtNvnivmnyirnamvrlled
interface signature	HTKMSKTQQRRKSRERI/HTKMSKTQQQRRKSRERN

Estimated binding specificities ?

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# IC=26.217 IC/col=0.771 n_of_columns=34

specificity:

A |  93   0  68  24  24  24   3   0   0   0  96   0  96  58  24  24  24  24  24   4   0   0  96   0  96   0   0  84  24  24  24   6  86   4
C |   0   0   3  24  24  24   1  96   0   0   0   0   0   6  24  24  24  24  24   6  96   0   0   0   0  96   0   3  24  24  24   3   3   6
G |   3   0  16  24  24  24   0   0  96   0   0   0   0  21  24  24  24  24  24  77   0   0   0   0   0   0  96   3  24  24  24   0   4   0
T |   0  96   9  24  24  24  92   0   0  96   0  96   0  11  24  24  24  24  24   9   0  96   0  96   0   0   0   6  24  24  24  87   3  86

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updated Mon Jan 5 00:44:16 2026