2itl_AB : 3D-footprint complex

structure name	THE ORIGIN BINDING DOMAIN OF THE SV40 LARGE T ANTIGEN BOUND TO THE FUNCTIONAL PEN PALINDROME DNA (23 BP)
reference	Bochkareva et al. 'Embo 25 5961 2006
source	Simian virus 40
experiment	X-ray (resolution=1.65, R-factor=?)
structural superfamily	Origin of replication-binding domain, RBD-like;
reference complex	2itl_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2itl_A interface=20,21,22,71, dpkdfpsellsflshavfsNRTlacfaiyttkekaallykkimekysvtfisrhnsynhnilffltphrhRvsainnyaqklctfsflickgvnkeylmysaltrdpfsvieeslpgglk > 2itl_B interface=18,19,20,70, pkdfpsellsflshavfSNRtlacfaiyttkekaallykkimekysvtfisrhnsynhnilffltphrhRvsainnyaqklctfsflickgvnkeylmysaltrdpfsvieeslp
interface signature	NRTR/SNRR

Estimated binding specificities ?

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# IC=10.000 IC/col=0.588 n_of_columns=17

specificity:

A |  66   0  96   0   0   6  24  24  24  24  24  24   0   0   6  24  15
C |  12   0   0   0   0  78  24  24  24  24  24  24   0   0  76  24  12
G |  12  96   0  96  96   6  24  24  24  24  24  24  96  96   6  24  12
T |   6   0   0   0   0   6  24  24  24  24  24  24   0   0   8  24  57

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updated Mon Jan 5 00:54:00 2026