2kkf_A : 3D-footprint complex

structure name	SOLUTION STRUCTURE OF MLL CXXC DOMAIN IN COMPLEX WITH PALINDROMIC CPG DNA (HISTONE-LYSINE N-METHYLTRANSFERASE HRX)
source	HOMO SAPIENS
experiment	NMR
sequence family	CXXC zinc finger domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2kkf_A interface=4,37,39,40,41,44, kkgRrsrrcgqcpgcqvpedcgvctncldkpkfggrNiKKQccKmrkcqnlqwmpsk
interface signature	RNKKQK

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5

specificity:

A |  13   0   0   0  54
C |  13  96   0  96  16
G |  57   0  96   0  13
T |  13   0   0   0  13

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Dendrogram of similar interfaces ?

matrix format

  
  RC--NTICKGKGQGKT   L                 +-2kkf_A    
                         +-------------2 
  --------SGKGQC--       !             +-3pta_A    
                       --3 
  --------KTKGQC--   L   !              +4nw3_A    
                         +--------------1 
  --RT----MAKGQG--   L                  +6asb_F

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updated Sat Aug 2 02:47:58 2025