2pi5_A : 3D-footprint complex

structure name	T7 RNA POLYMERASE COMPLEXED WITH A PHI10 PROMOTER (DNA-directed RNA polymerase)
reference	Kennedy et al. J.Mol.Biol. 370 256 2007
source	Enterobacteria phage T7
experiment	X-ray (resolution=2.90, R-factor=0.249)
structural superfamily	DNA/RNA polymerases;
sequence family	DNAdependent RNA polymerase;
reference complex	1msw_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2pi5_A interface=75,77,210,216,219,725,727,735,737,739, iakndfsdielaaipfntladhygerlareqlalehesyemgearfrkmfplittllpkmiarindwfeevkakRgKrptafqflqeikpeavayitikttlacltsadnttvqavasaigraiedearfgrirdleakhfkknveeqlnkrvghvykkafmqvveadmlskgllggeawsswhkedsihvgvrciemliestgmvslhRqnagvVgqDsetielapeyaeaiatragalagispmfqpcvvppkpwtgitgggywangrrplalvrthskkalmryedvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelpmkpedidmnpealtawkraaaavyrkdkarksrrislefmleqankfanhkaiwfpynmdwrgrvyavsmfnpqgndmtkglltlakgkpigkegyywlkihgancagvdkvpfperikfieenhenimacaksplentwwaeqdspfcflafcfeyagvqhhglsyncslplafdgscsgiqhfsamlrdevggravnllpsetvqdiygivakkvneilqadaingtdnevvtvtdentgeisekvklgtkalagqwlaygvtrsvtkrsvmtlaygskefgfrqqvledtiqpaidsgkglmftqpnqaagymakliwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrkrcavhwvtpdgfpvwqeykkpiqtRlNlmflgqfRlQpTintnkdseidahkqesgiapnfvhsqdgshlrktvvwahekygiesfalihdsfgtipadaanlfkavretmvdtyescdvladfydqfadqlhesqldkmpalpakgnlnlrdilesdfafa
interface signature	RKRVDRNRQT

Estimated binding specificities ?

readout + contact

# IC=10.925 IC/col=0.840 n_of_columns=13

specificity:

A |   0  74  69  24  66  24   1  70   0   0   0  96   0
C |   5   7  12  24  10  24   0   5  96   0  96   0  96
G |   0   5  10  24  10  24   5   5   0   0   0   0   0
T |  91  10   5  24  10  24  90  16   0  96   0   0   0

scan!

home
updated Sat Aug 2 03:00:58 2025