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legend  pdf

structure nameSTRUCTURE OF THE WILMS TUMOR SUPPRESSOR PROTEIN ZINC FINGER DOMAIN BOUND TO DNA
(Wilms tumor 1)
referenceDebler et al. J.Mol.Biol. 372 1227 2007
sourceHomo sapiens
experimentX-ray (resolution=3.15, R-factor=0.236)
structural superfamilyC2H2 and C2HC zinc fingers;
sequence familyZinc finger, C2H2 type;
redundant complexes2jp9 2jpa
reference complex2jpa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDRRDHRDER

Estimated binding specificities ?

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# IC=11.300 IC/col=1.130 n_of_columns=10 specificity:   
A |  48   0   0   0   0   0   0   0  16   0
C |  16  96   0  96  96  96  96  96  16  96
G |  16   0  96   0   0   0   0   0  64   0
T |  16   0   0   0   0   0   0   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ACYCPCPCYCRG--DA--RG--RG--DCHG----------RG--DCECRG   L               +-------2prt_A    
                                                           +-----------5 
  ----------QG--RGHTMG--QG----LGLC------TTRG--------   L   !           +-------5yel_A    
                                                           ! 
  ----------RGSTDAHARG--RGSTDCHG----TT----RG--DAEGRG   L   !                   +5kl3_A    
                                                           !           +-------2 
  --------------HCHGRG--TA--ACNA----KGRG------------   L --8        +--4       +1tf6_A    
                                                           !        !  ! 
  ----------LT--ETYC----NTYGQG----------------------   L   !        !  +-------4f6m_A    
                                                           !    +---6 
  ----------QA--TTNA--STQAQTATST--NTAT----TTLAHGTCRG   L   !    !   !          +1g2f_F    
                                                           !    !   !      +---1 
  ----------QA--ATHG----RG--DCNA----TT----RGRTDAAT--   L   +----7   +------3   +2i13_A    
                                                                !          ! 
  ------------TCYCKARG--QA----TC----------RA--SCDCVT   L        !          +---5yeg_A    
                                                                ! 
  ----------RG--DGECRG--RGSGDCHA--------------------   L        +--------------2wbs_A    
                                                         

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updated Thu Sep 12 16:28:16 2024