2qkb_AB : 3D-footprint complex

structure name	HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 20-MER RNA/DNA HYBRID
reference	Gaidamakov et al. Mol.Cell 28 264 2007
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Ribonuclease H-like;
reference complex	8swb_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2qkb_A interface=19,21,50,51,81,89,101, gshmgdfvvvytdgccssNgRrrpragigvywgpghplnvgirlpgrqtNQraeihaackaieqaktqninklvlytnsmFtingitnWvqgwkkngwktSagkevinkedfvalerltqgmdiqwmhvpghsgfigneeadrlaregakqs > 2qkb_B interface=18,48,49,79,87,98,99, shmgdfvvvytdgccssNrrrpragigvywgpghplnvgirlpgrqtNQraeihaackaieqaktqninklvlytnsmFtingitnWvqgwkkngwkTSagkevinkedfvalerltqgmdiqwmhvpghsgfigneeadrlaregakqs
interface signature	NRNQFWS/NNQFWTS

Estimated binding specificities ?

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# IC=12.787 IC/col=0.984 n_of_columns=13

specificity:

A |  96  96   0  10  89   0  10   5   0   0  10  10   0
C |   0   0   0  66   0   0  11   3   0   0  61  11  96
G |   0   0   0  10   4  96  65   3  96   0  12  65   0
T |   0   0  96  10   3   0  10  85   0  96  13  10   0

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updated Tue Jul 29 18:40:17 2025