interface graph thumbnail
legend  pdf

structure nameHUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 20-MER RNA/DNA HYBRID
referenceGaidamakov et al. Mol.Cell 28 264 2007
sourceHomo sapiens
experimentX-ray (resolution=2.40, R-factor=?)
structural superfamilyRibonuclease H-like;
reference complex8swb_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNRNQFWS/NNQFWTS

Estimated binding specificities ?

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# IC=12.921 IC/col=0.994 n_of_columns=13 specificity:   
A |  96  96   0   9  87   0   9   3   0   0  13   9   0
C |   0   0   0  69   3   0   9   3   0   0  66   9  96
G |   0   0   0   9   3  96  66   4  96   0   8  66   0
T |   0   0  96   9   3   0  12  86   0  96   9  12   0
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updated Wed Jun 24 13:43:00 2026