2up1_A : 3D-footprint complex

structure name	STRUCTURE OF UP1-TELOMERIC DNA COMPLEX (PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1)
reference	Hayashi et al. 'Genes 13 1102 1999
source	HOMO SAPIENS
experiment	X-ray (resolution=2.10, R-factor=0.195)
structural superfamily	RNA-binding domain, RBD;
sequence family	RNA recognition motif aka RRM, RBD, or;
reference complex	8rzv_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2up1_A interface=4,5,8,10,35,37,39,52,75,78,80,82,83,85,88,94, kepEQlrKlFigglsfettdeslrshfeqwgtltDcVvMrdpntkrsrgfgFvtyatveevdaamnarphkvdgRvvEpKrAVsRedSqrpgaHltvkkifvggikedteehhlrdyfeqygkievieimtdrgsgkkrgfafvtfddhdsvdkiviqkyhtvnghncevrkalskqemasas
interface signature	EQKFDVMFREKAVRSH

Estimated binding specificities ?

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# IC=6.969 IC/col=0.996 n_of_columns=7

specificity:

A |   0  96   0   0  24   0  12
C |   0   0   0   0  24   0  12
G |   0   0  96  96  24   0  12
T |  96   0   0   0  24  96  60

scan!

Dendrogram of similar interfaces ?

matrix format

  
  EGQGKGFA----------DGVGMG------------FGRTETKTAGVA--RG--SGHA   L              +----------------2up1_A    
                                                                              ! 
  ----DGICLG--WG------QGKT--LT--KG--FGFGRG----PCNC----------   L   +----------3               +4y0f_A    
                                                                   !          !           +---1 
  ----RC----NU------------------KUNU--FC------PC------DC----       !          +-----------2   +3vaj_B    
                                                                 --4                      ! 
  ----TAFCSG----------LAKATG--TGSG--VGFA----RAEC--ACKC------   L   !                      +----5tkz_B    
                                                                   ! 
  --------------KGYG----------------------------------------   L   +---------------------------2ayg_A

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updated Thu Sep 12 16:32:49 2024