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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

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updated Mon Jan 5 02:03:43 2026

structure name	PROMISCUITY AND SPECIFICITY IN DNA BINDING TO SSB: INSIGHTS FROM THE STRUCTURE OF THE MYCOBACTERIUM SMEGMATIS SSB-SSDNA COMPLEX
reference	Manjunath et al.
source	Mycobacterium smegmatis
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Nucleic acid-binding proteins;
reference complex	3a5u_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3a5u_A interface=14,15,18,32,55,56,60,61,85,86,88,89,90,96,98,99,103,104, magdttitvvgnlTAdpElrftpsgaavanfTvastprmfdrqsgewkdgealfLRcniWReaaenvaesltrgsrvivtgrlkQRsFTRegekrTvVEvevDEigpslryatakvnk > 3a5u_B interface=16,18,19,20,26,27,38,49,51,56,60,64,68,80,81,91,92,104, magdttitvvgnltaDpELRftpsgAAvanftvastpRmgewkdgealFlRcniwReaaEnvaEsltRgsrvivtgrlkQRsfetrekrtVVevevdeigpslRyatakvnk