3dzu_AD : 3D-footprint complex

structure name	INTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH BVT.13, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
reference	Rastinejad et al. Nature 456 350 2008
source	HOMO SAPIENS
experiment	X-ray (resolution=3.20, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3dzu_A interface=22,25,29,30, khicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeerqranedmpverileaeladpvtnicqaadkqlftlvewakriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmeml > 3dzu_D interface=22,25,29,30,77, aiecrvcgdkasgfhygvhacEgcKgffRRtirlkliydrcdlncrihkksrnkcqycrfqkclavgmshnairfgRmpqaekekllaeissdidqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly
interface signature	EKKR/EKRRR

Estimated binding specificities ?

readout + contact

# IC=11.231 IC/col=0.661 n_of_columns=17

specificity:

A |  93  69  24  24  61   0   0   2  24  72  24  24   0   0   8   0  78
C |   3   8  24  24  11   0   0   2  24  11  24  24   0   0  16  96  11
G |   0   8  24  24  13  96  96   5  24   8  24  24  96  96  11   0   5
T |   0  11  24  24  11   0   0  87  24   5  24  24   0   0  61   0   2

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updated Mon Sep 9 17:28:34 2024