interface graph thumbnail
legend  pdf

structure nameINTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH BVT.13, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
(PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA)
referenceRastinejad et al. Nature 456 350 2008
sourceHOMO SAPIENS
experimentX-ray (resolution=3.20, R-factor=?)
structural superfamilyNuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains; Ligandbinding domain of nuclear hormon;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKRRR

Estimated binding specificities ?

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# IC=8.607 IC/col=0.782 n_of_columns=11 specificity:   
A |  64  96  80  24  24  91   0   0   0   5  85
C |  10   0   5  24  24   0   1   0   0  58   0
G |  10   0   6  24  24   5  90  96   0  10   6
T |  12   0   5  24  24   0   5   0  96  23   5
scan!

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updated Sat Aug 2 03:43:30 2025