interface graph thumbnail
legend  pdf

structure nameINTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH BVT.13, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
(PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA)
referenceRastinejad et al. Nature 456 350 2008
sourceHOMO SAPIENS
experimentX-ray (resolution=3.20, R-factor=?)
structural superfamilyNuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains; Ligandbinding domain of nuclear hormon;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKRRR

Estimated binding specificities ?

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# IC=8.690 IC/col=0.790 n_of_columns=11 specificity:   
A |   4  14  96   0   1   4  24  24   4   0  16
C |   7   4   0  96  91   4  24  24   4   0   4
G |   4  69   0   0   4   4  24  24   4   0   4
T |  81   9   0   0   0  84  24  24  84  96  72
scan!

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updated Mon Dec 16 20:43:40 2024