3dzy_AD : 3D-footprint complex

structure name	INTACT PPAR GAMMA - RXR ALPHA NUCLEAR RECEPTOR COMPLEX ON DNA BOUND WITH ROSIGLITAZONE, 9-CIS RETINOIC ACID AND NCOA2 PEPTIDE
reference	Rastinejad et al. Nature 456 350 2008
source	HOMO SAPIENS
experiment	X-ray (resolution=3.10, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3dzy_A interface=22,25,29,30, khicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeerqrgkdrnenevestssanedmpverileaelapvtnicqaadkqlftlvewakriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmeml > 3dzy_D interface=22,25,29,30,75,77, aiecrvcgdkasgfhygvhacEgcKgffRRtirlkliydrcdlncrihkksrnkcqycrfqkclavgmshnairFgRmpqaekekllaeissdidqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgeevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqeiykdly
interface signature	EKKR/EKRRFR

Estimated binding specificities ?

readout + contact

# IC=11.120 IC/col=0.618 n_of_columns=18

specificity:

A |   4   0  24   0  24  24  24   4   0  79   0   0   9  24  24  24   4   4
C |   7   0  24  96  24  24  24   4   0   4  96  96   9  24  24  24   7   4
G |   4  96  24   0  24  24  24   0  96   9   0   0   6  24  24  24   9   7
T |  81   0  24   0  24  24  24  88   0   4   0   0  72  24  24  24  76  81

scan!

home
updated Wed Jun 24 15:30:37 2026