3e2e_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AN INTERMEDIATE COMPLEX OF T7 RNAP AND 7NT OF RNA (DNA-directed RNA polymerase)
reference	Durniak et al. Science 322 553 2008
source	Bacteriophage T7
experiment	X-ray (resolution=3.00, R-factor=0.243)
structural superfamily	DNA/RNA polymerases;
sequence family	DNAdependent RNA polymerase;
reference complex	1msw_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3e2e_A interface=74,76,113,117,173,177,198,204,207,340,341,593,596,597,600,620,695,697,705,707,709,710,711, kndfsdielaaipfntladhygerlareqlalehesyemgearfrkmferlittllpkmiarindwfeevkakRgKrptafqflqeikpeavayitikttlacltsadnttvQavaSaigraiedearfgrirdleakhfkknvykkafmqvveadmlskgllggeawsswhKedsIhvgvrciemliestgmvslhRqnagvVgqDsetielapeyaeaiislmfqpcvvppkpwtgitgggywangrrplalvrthskkalmryedvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelpmkpdmnpealtawkraaaavYRkdkarksrrislefmleqankfanhkaiwfpynmdwrgrvyavsmfnpqgndmtkglltlakgkpigkegyywlkihgancagvdkvpfperikfieenhenimacaksplentwwaeqdspfcflafcfeyagvqhhglsyncslplafdgscsgiqhfsamlrdevggravnllpsetvqdiygivakkvneilqadaingtdnevvtvtisekvklgtkalagqwlaygvtrsvtkrsvmtlaygskeFgfRQqvLedtiqpaidsgkglmftqpNqaagymakliwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrkrcavhwvtpdgfpvwqeykkpiqtRlNlmflgqfRlQpTINtnkdseidahkqesgiapnfvhsqdgshlrktvvwahekygiesfalihdsfgtipadaanlfkavretmvdtyescdvladfydqfadqlhesqldkmpalpakgnlnlrdilesdfafa
interface signature	RKQSKIRVDYRFRQLNRNRQTIN

Estimated binding specificities ?

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# IC=19.010 IC/col=0.950 n_of_columns=20

specificity:

A |   0   0   0  24  24  24  96   0   0   0  96   0   0   0  15   5  55   5   0  96
C |   0   0  96  24  24  24   0   0   0   0   0   0   0  96   5   5  16  16   0   0
G |  96   0   0  24  24  24   0  96   0  96   0  96   0   0  60   5  10  15   0   0
T |   0  96   0  24  24  24   0   0  96   0   0   0  96   0  16  81  15  60  96   0

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updated Sat Aug 2 03:44:52 2025