3e2e_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AN INTERMEDIATE COMPLEX OF T7 RNAP AND 7NT OF RNA (DNA-directed RNA polymerase)
reference	Durniak et al. Science 322 553 2008
source	Bacteriophage T7
experiment	X-ray (resolution=3.00, R-factor=0.243)
structural superfamily	DNA/RNA polymerases;
sequence family	DNAdependent RNA polymerase;
reference complex	1msw_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3e2e_A interface=74,76,113,117,173,177,198,204,207,340,341,382,585,588,590,593,596,597,598,600,620,695,697,705,707,709,710,711,729,733, kndfsdielaaipfntladhygerlareqlalehesyemgearfrkmferlittllpkmiarindwfeevkakRgKrptafqflqeikpeavayitikttlacltsadnttvQavaSaigraiedearfgrirdleakhfkknvykkafmqvveadmlskgllggeawsswhKedsIhvgvrciemliestgmvslhRqnagvVgqDsetielapeyaeaiislmfqpcvvppkpwtgitgggywangrrplalvrthskkalmryedvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelpmkpdmnpealtawkraaaavYRkdkarksrrislefmleqankfanhkaiwfpynmdwrgrvYavsmfnpqgndmtkglltlakgkpigkegyywlkihgancagvdkvpfperikfieenhenimacaksplentwwaeqdspfcflafcfeyagvqhhglsyncslplafdgscsgiqhfsamlrdevggravnllpsetvqdiygivakkvneilqadaingtdnevvtvtisekvklgtkalagqwlaygvtrsvtkrsvmTlaYgSkeFgfRQQvLedtiqpaidsgkglmftqpNqaagymakliwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrkrcavhwvtpdgfpvwqeykkpiqtRlNlmflgqfRlQpTINtnkdseidahkqesgiaPnfvHsqdgshlrktvvwahekygiesfalihdsfgtipadaanlfkavretmvdtyescdvladfydqfadqlhesqldkmpalpakgnlnlrdilesdfafa
interface signature	RKQSKIRVDYRYTYSFRQQLNRNRQTINPH

Estimated binding specificities ?

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# IC=19.807 IC/col=0.990 n_of_columns=20

specificity:

A |   0  96  69   8  82  11   0  96   0   0   0  96   0   0  24  24  13   0   0   0
C |   0   0   8   8   4  69   0   0  96   0  96   0  96   0  24  24  13   0   0  96
G |   0   0  11  11   6   8  96   0   0   0   0   0   0   0  24  24  13  96  96   0
T |  96   0   8  69   4   8   0   0   0  96   0   0   0  96  24  24  57   0   0   0

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updated Thu Jan 8 21:25:16 2026