3e3j_C : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AN INTERMEDIATE COMPLEX OF T7 RNAP AND 8NT OF RNA (DNA-directed RNA polymerase)
reference	Durniak et al. Science 322 553 2008
source	Bacteriophage T7
experiment	X-ray (resolution=6.70, R-factor=0.395)
structural superfamily	DNA/RNA polymerases;
sequence family	DNAdependent RNA polymerase;
reference complex	1msw_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3e3j_C interface=72,74,194,200,203,379,383,594,597,696,698,706,708,710,734, kndfsdielaaipfntladhygerlareqlalehesyemgearfrkmflittllpkmiarindwfeevkakRgKrptafqflqeikpeavayitikttlacltsadnttvqavasaigraiedearfgrirdleakhfkknvkafmqvveadmlskgllggeawsswhkedsihvgvrciemliestgmvslhRqnagvVgqDsetielapeyaeaiagislmfqpcvvppkpwtgitgggywangrrplalvrthskkalmryedvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelpmkpedidmnpealtawkraaaavyrkdkarksrrislefmleqankfanhkaiwfpynmdwRgrvYavsmfnpqgndmtkglltlakgkpigkegyywlkihgancagvdkvpfperikfieenhenimacaksplentwwaeqdspfcflafcfeyagvqhhglsyncslplafdgscsgiqhfsamlrdevggravnllpsetvqdiygivakkvneilqadaingtdnevvtvtisekvklgtkalagqwlaygvtrsvtkrsvmtlaygskeFgfRqqvledtiqpaidsgkglmftqpnqaagymakliwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrkrcavhwvtpdgfpvwqeykkpiqtRlNlmflgqfRlQpTintnkdseidahkqesgiapnfvHsqdgshlrktvvwahekygiesfalihdsfgtipadaanlfkavretmvdtyescdvladfydqfadqlhesqldkmpalpakgnlnlrdilesdfafa
interface signature	RKRVDRYFRRNRQTH

Estimated binding specificities ?

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# IC=13.549 IC/col=0.677 n_of_columns=20

specificity:

A |   5  80  24  10  64  24  10  90   0   0   0  96   1  96  24  24  24  24  24   0
C |   6   6  24  10  12  24   0   6  96   0  96   0  85   0  24  24  24  24  24  96
G |   0   5  24   7  10  24  85   0   0   0   0   0  10   0  24  24  24  24  24   0
T |  85   5  24  69  10  24   1   0   0  96   0   0   0   0  24  24  24  24  24   0

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updated Thu Sep 12 17:06:15 2024