3e3j_C : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AN INTERMEDIATE COMPLEX OF T7 RNAP AND 8NT OF RNA (DNA-directed RNA polymerase)
reference	Durniak et al. Science 322 553 2008
source	Bacteriophage T7
experiment	X-ray (resolution=6.70, R-factor=0.395)
structural superfamily	DNA/RNA polymerases;
sequence family	DNAdependent RNA polymerase;
reference complex	1msw_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3e3j_C interface=72,74,194,200,203,379,383,594,597,696,698,706,708,710,734, kndfsdielaaipfntladhygerlareqlalehesyemgearfrkmflittllpkmiarindwfeevkakRgKrptafqflqeikpeavayitikttlacltsadnttvqavasaigraiedearfgrirdleakhfkknvkafmqvveadmlskgllggeawsswhkedsihvgvrciemliestgmvslhRqnagvVgqDsetielapeyaeaiagislmfqpcvvppkpwtgitgggywangrrplalvrthskkalmryedvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelpmkpedidmnpealtawkraaaavyrkdkarksrrislefmleqankfanhkaiwfpynmdwRgrvYavsmfnpqgndmtkglltlakgkpigkegyywlkihgancagvdkvpfperikfieenhenimacaksplentwwaeqdspfcflafcfeyagvqhhglsyncslplafdgscsgiqhfsamlrdevggravnllpsetvqdiygivakkvneilqadaingtdnevvtvtisekvklgtkalagqwlaygvtrsvtkrsvmtlaygskeFgfRqqvledtiqpaidsgkglmftqpnqaagymakliwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrkrcavhwvtpdgfpvwqeykkpiqtRlNlmflgqfRlQpTintnkdseidahkqesgiapnfvHsqdgshlrktvvwahekygiesfalihdsfgtipadaanlfkavretmvdtyescdvladfydqfadqlhesqldkmpalpakgnlnlrdilesdfafa
interface signature	RKRVDRYFRRNRQTH

Estimated binding specificities ?

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# IC=14.517 IC/col=0.726 n_of_columns=20

specificity:

A |   0  67  24  24  24  24   0   0   0   0  96   0   0   0  24   9  76  24   9  91
C |   0  11  24  24  24  24  96  14   0   0   0   0   0  86  24  11   4  24   0   0
G |   0   9  24  24  24  24   0  81   0  96   0  96   4   0  24   9   7  24   6   1
T |  96   9  24  24  24  24   0   1  96   0   0   0  92  10  24  67   9  24  81   4

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updated Thu Jan 8 21:25:46 2026