interface graph thumbnail
legend  pdf

structure nameCPRK OCPA DNA COMPLEX
(Cyclic nucleotide-binding protein)
referenceMol.Microbiol. 70 151 2008
sourceDesulfitobacterium hafniense
experimentX-ray (resolution=1.80, R-factor=0.219)
structural superfamilycAMP-binding domain-like;"Winged helix" DNA-binding domain;
sequence familyCyclic nucleotidebinding domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHHVTSY

Estimated binding specificities ?

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# IC=5.300 IC/col=0.883 n_of_columns=6 specificity:   
A |   9   0  67  96   9   0
C |   9   0  11   0   9   0
G |  11   0   9   0  11  96
T |  67  96   9   0  67   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: CPRK
TTAATPubMed3e6c_C(1.20e-07)
ATTAAPubMed3e6c_C(1.20e-07)
ACTAAPubMed3e6c_C(2.63e-03)
ATCAAPubMed3e6c_C(2.85e-03)
TTGATPubMed3e6c_C(2.85e-03)

Dendrogram of similar interfaces ?

matrix format
  
  ----HTHTVATAST----YA   L                    +------3e6c_C    
                                  +-----------1 
  ----HT--STATSTRG----   L   +----2           +------5lej_A    
                             !    ! 
  ----ITRGECSCSGKG----   L --3    +------------------5i2d_R    
                             ! 
  ETNTSCRGHC--RT--QA--   L   +-----------------------5d4s_B    
                           

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updated Fri Sep 13 16:59:09 2024