3g0q_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MUTY BOUND TO ITS INHIBITOR DNA (AG-specific adenine glycosylase)
reference	Verdine et al. Proc.Natl.Acad.Sci.Usa 106 18497 2009
source	Bacillus Stearothermophilus
experiment	X-ray (resolution=2.20, R-factor=0.246)
structural superfamily	Nudix;DNA-glycosylase;
sequence family	HhHGPD superfamily base excision DNA r; Helixhairpinhelix motif; Ironsulfur binding domain of endonucle;
redundant complexes	1vrl 1rrq 3fsp 3fsq 1rrs
reference complex	8dvp_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3g0q_A interface=40,42,80,156,292,293, parefqrdlldwfarerrdlpwrkdrdpykvwvsevmlqQtRvetvipyfeqfidrfptlealadadedevlkaweglgYysrvrnlhaavkevktryggkvpddpdefsrlkgvgpytvgavlslaygvpepavdgnvmrvlsrlflvtddiakCstrkrfeqivreimayenpgafnealielgalvctprrpscllcpvqaycqafaegvaeelpvkmvkqvplavavladdegrvlirkrdstgllanlwefpscetdgadgkekleqmvglqveltepivsfehafSHlvwqltvfpgrlvhggpveepyrlapedelkayafpvshqrvwreykewas
interface signature	QRYCSH

Estimated binding specificities ?

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# IC=3.137 IC/col=0.627 n_of_columns=5

specificity:

A |  16  10   0  24   0
C |  45  63  96  24   0
G |  16  13   0  24  96
T |  19  10   0  24   0

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Dendrogram of similar interfaces ?

matrix format

  
  QC--RGYC------------CASGHC   L              +-------------3g0q_A    
                                   +----------2 
  QGCGTA--------------------       !          !     +-------1orn_A    
                                 --3          +-----1 
  NG--RG--FGRC--------------       !                +-------4ejy_A    
                                   ! 
  ------------IAQTNAMC------   L   +------------------------2h1k_B

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updated Thu Sep 12 17:10:28 2024