interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF MUTY BOUND TO ITS INHIBITOR DNA
(AG-specific adenine glycosylase)
referenceVerdine et al. Proc.Natl.Acad.Sci.Usa 106 18497 2009
sourceBacillus Stearothermophilus
experimentX-ray (resolution=2.20, R-factor=0.246)
structural superfamilyNudix;DNA-glycosylase;
sequence familyHhHGPD superfamily base excision DNA r; Helixhairpinhelix motif; Ironsulfur binding domain of endonucle;
redundant complexes1vrl 1rrq 3fsp 3fsq 1rrs
reference complex8dvp_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQRYCSH

Estimated binding specificities ?

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# IC=3.137 IC/col=0.627 n_of_columns=5 specificity:   
A |  16  10   0  24   0
C |  45  63  96  24   0
G |  16  13   0  24  96
T |  19  10   0  24   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  QC--RGYC------------CASGHC   L              +-------------3g0q_A    
                                   +----------2 
  QGCGTA--------------------       !          !     +-------1orn_A    
                                 --3          +-----1 
  NG--RG--FGRC--------------       !                +-------4ejy_A    
                                   ! 
  ------------IAQTNAMC------   L   +------------------------2h1k_B    
                                 

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updated Mon Dec 18 07:56:11 2023