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legend  pdf

structure nameTERNARY COMPLEX OF DNA POLYMERASE IOTA:DNA:DGTP WITH AN ABASIC SITE AT THE TEMPLATING POSITION
(DNA polymerase iota)
referenceAggarwal et al. Structure 17 530 2009
sourceHomo sapiens
experimentX-ray (resolution=2.08, R-factor=0.225)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
multimeric complexes1t3n_AB
redundant complexes2alz 2flp 3g6y 2fln 1t3n 1zet 3epi 2dpi 2fll 3g6v 2dpj 3epg
reference complex3q8p_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  YG------------------ST--EG----RGSG--------                             +---3g6x_A    
                                                                     +---3 
  ----MASA----AAPCIC------EG--------TG----RG                         !   +---2oh2_B    
                                                               +-----4 
  ----AT--------PC----ST--------------RARTRG                   !     !     +-1jx4_A    
                                                               !     !   +-1 
  --------------FG----------ETYA------------       +-----------5     +---2 +-3gqc_D    
                                                   !           !         ! 
  --HA----------WG----------DT--------------       !           !         +---2aq4_A    
                                                 --6           ! 
  ----SG--SGRGMG--------MT------------------       !           +-------------2r8j_B    
                                                   ! 
  ------------------RT----------------------       +-------------------------1lb2_B    
                                                 

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updated Mon Dec 18 07:57:06 2023