interface graph thumbnail
legend  pdf

structure nameSEQUENCE-MATCHED MUTM INTERROGATION COMPLEX 4 (IC4)
(DNA glycosylase)
referenceVerdine et al. Nature 462 762 2009
sourceGeobacillus stearothermophilus
experimentX-ray (resolution=1.78, R-factor=0.190)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyFormamidopyrimidineDNA glycosylase N; FormamidopyrimidineDNA glycosylase H2; Zinc finger found in FPG and IleRS;
redundant complexes3gq3
reference complex3u6p_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRMRFR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |  13   0   0   0  13
C |  54   0  96   0  16
G |  16   0   0  96  54
T |  13  96   0   0  13
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updated Thu Jan 8 21:37:03 2026