interface graph thumbnail
legend  pdf

structure nameSEQUENCE-MATCHED MUTM INTERROGATION COMPLEX 5 (IC5)
(DNA glycosylase)
referenceVerdine et al. Nature 462 762 2009
sourceGeobacillus stearothermophilus
experimentX-ray (resolution=1.90, R-factor=0.204)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyFormamidopyrimidineDNA glycosylase N; FormamidopyrimidineDNA glycosylase H2; Zinc finger found in FPG and IleRS;
reference complex3u6p_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRRFR

Estimated binding specificities ?

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# IC=3.107 IC/col=0.777 n_of_columns=4 specificity:   
A |  18  10   0   0
C |  42  10   0   0
G |  18  63  96  96
T |  18  13   0   0
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updated Thu Sep 12 17:13:35 2024