3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

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updated Fri Dec 13 15:23:14 2024

structure name	THREE-DIMENSIONAL EM STRUCTURE OF AN INTACT ACTIVATOR-DEPENDENT TRANSCRIPTION INITIATION COMPLEX
source	ESCHERICHIA COLI / ESCHERICHIA COLI K-12
experiment	NMR
structural superfamily	Insert subdomain of RNA polymerase alpha subunit;C-terminal domain of RNA polymerase alpha subunit;RBP11-like subunits of RNA polymerase;cAMP-binding domain-like;"Winged helix" DNA-binding domain;P-loop containing nucleoside triphosphate hydrolases;Putative DNA-binding domain;beta and beta-prime subunits of DNA dependent RNA-polymerase;Nucleic acid-binding proteins;Rho N-terminal domain-like;Probable bacterial effector-binding domain;Homeodomain-like;lambda repressor-like DNA-binding domains;CheY-like;C-terminal effector domain of the bipartite response regulators;
reference complex	3iyd_A 3iyd_H 5nss_G 6ldi_G 6vu3_A 6vz3_A 6xas_B 6xh7_H 6xl5_H 7c97_K 7vwz_G 7w5x_A 8igr_C 8jo2_H 8u3b_G 8upo_A 8y6u_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3iyd_A interface=291, qgsvteflkprlvdieqvssthakvtleplergfghtlgnalrrillssmpgcavteveidgvlheystkegvqedileillnlkglavrvqgkdeviltlnksgigpvtaadithdgdveivkpqhvichltdenasismrikvqrgrgyvpastrierpigrllvdacyspveriaynveaarveqrtdldklviemetngtidpeeairraatilaeqleafvdlrdvrqpevkeekpefdpillrpvddleltvrsanclkaeaihyigdlvqrtevellktpnlgKkslteikdvlasrglslgmrlenwppasiad > 3iyd_C interface=54,170,171,174,191,289,290,373,987,1019, rirkdfgkrpqvldvpyllsiqldsfqkfieqdpegqygleaafrsvfpiqsySgnselqyvsyrlgepvfdvqecqirgvtysaplrvklrlviyereapegtvkdikeqevymgeiplmtdngtfvingtervivsqlhrspgvffdsdkgkthssgkvlynariipYRgsWldfefdpkdnlfvridRrrklpatiilralnytteqildlffekvdllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalveiyrmmrpgepptreaaeslfenlFFsedrydlsavgrmkfnrsllreeiegsgilskddiidvmkklidirngkgevddidhlgnrrirsvgemaenqfrvglvrveRavkerlslgdldtlmpqdminakpisaavkeffgssqlsqfmdqnnplseithkrrisalgpggltreragfevrdvhpthygrvcpietpegpniglinslsvyaqtneygfletpyrkvtdgvvtdeihylsaieegnyviaqansnldeeghfvedlvtcrskgesslfsrdqvdymdvstqqvvsvgaslipflehddanralmganmqrqavptlradkplvgtgmeravavdsgvtavakrggvvqyvdasrivikvnedemypgeagidiynltkytrsnqntcinqmpcvslgepvergdvladgpstdlgelalgqnmrvafmpwngynfedsilvservvqedrfttihiqelacvsrdtklgpeeitadipnvgeaalskldesgivyigaevtggdilvgkvtpkgetqltpeekllraifgekasdvkdsslrvpngvsgtvidvqvftrdgvekdlapgvlkivkvylavkrriqpgdkmagrhgnkgviskinpiedmpydengtpvdivlnplgvpsrmnigqilethlgmaakgigmpiatpvfdgakeaeikellklgdlptsgqirlydgrtgeqferpvtvgymymlklnhlvDdkmharstgsyslvtqqplggkaqfggqrfgEmevwaleaygaaytlqemltvksddvngrtkmyknivdgnhqmepgmpesfnvllkeirslginielede > 3iyd_D interface=305,320,323,325,326,329,338,412,413,451,784,788, eefdaikialaspdmirswsfgevkkpetinyrtfkperdglfcarifgpvkdyeclcgkykrlkhrgvicekcgvevtqtkvrrermghielasptahiwflkslpsrigllldmplrdiervlyfesyvvieggmtnlerqqilteeqyldaleefgdefdakmgaeaiqallksmdleqeceqlreelnetnsetkrkkltkriklleafvqsgnkpewmiltvlpvlppdlrplvpldggrfatsdlndlyrrvinrnnrlkrlldlaapdiivrnekrmlqeavdalldngrrgraitgSnkrplksladmikgKqgRfRQnlLgkrvdysgRsvitvgpylrlhqcglpkkmalelfkpfiygklelrglattikaakkmvereeavvwdildevirehpvllnrAPtlhrlgiqafepvliegkaiqlhplvcaaynadfdgdQmavhvpltleaqlearalmmstnnilspangepiivpsqdvvlglyymtrdcvnakgegmvltgpkeaerlyrsglaslharvkvriteyekdangelvaktslkdttvgrailwmivpkglpysivnqalgkkaiskmlntcyrilglkptvifadqimytgfayaarsgasvgiddmvipekkheiiseaeaevaeiqeqfqsglvtagerynkvidiwaaandrvskammdnlqtetvinrdgqeekqvsfnsiymmadsgargsaaqirqlagmrglmakpdgsiietpitanfreglnvlqyfisthgarkgladtalktansgyltRrlvDvaqdlvvteddcgthegimmtpvieggdvkeplrdrvlgrvtaedvlkpgtadilvprntllheqwcdlleensvdavkvrsvvscdtdfgvcahcygrdlarghiinkgeaigviaaqsigepgtqltmrtfhiggaasraaaessiqvknkgsiklsnvksvvnssgklvitsrntelklidefgrtkesykvpygavlakgdgeqvaggetvanwdphtmpvitevsgfvrftdmidgqtitrqtdeltglsslvvldsaertaggkdlrpalkivdaqgndvlipgtdmpaqyflpgkaivqledgvqissgdtlaripqesggtkditgglprvadlfearrpkepailaeisgivsfgketkgkrrlvitpvdgsdpyeemipkwrqlnvfegervergdvisdgpeaphdilrlrgvhavtryivnevqdvyrlqgvkindkhievivrqmlrkativnagssdflegeqveysrvkianreleangkvgatysrdllgitkaslatesfisaasfqettrvlteaavagkrdelrglkenvivgrlipagtgyayhqdrmrrraageapaap > 3iyd_F interface=262,264,265,296,297,301,322,323,325,326,371,452,453,454,456,457, megeidiakriedginqvqcsvaeypeaitylleqynrveaeearlsdlitgfvdpnaeedlaptathvgselsqedldidpelarekfaelraqyvvtrdtikakgrshataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveanlrlvisiakkYtNRglqfldliqegniglmkavdkfeyrrgykfSTyatWwirqaitrsiadqartiripVHmIEtinklnrisrqmlqemgreptpeelaermlmpedkirkvlkiakEpismetpigddedshlgdfiedttlelpldsatteslraathdvlagltareakvlrmrfgidmntdhtleevgkqfdvtRERiRQieakalrklrhpsrsevlrsfl > 3iyd_G interface=172,173,174,177, ptlewflshchihkypskstlihqgekaetlyyivkgsvavlikdeegkemilsylnqgdfigelglfeegqersawvraktacevaeisykkfrqliqvnpdilmrlsaqmarrlqvtsekvgnlafldvtgriaqtllnlakqpdamthpdgmqikitrqeigqivgcsRETvgRilkmledqnlisahgktivvygtr > 3iyd_H interface=18,162,171,172,173,174,177, ptlewflshchihkypsKstlihqgekaetlyyivkgsvavlikdeegkemilsylnqgdfigelglfeegqersawvraktacevaeisykkfrqliqvnpdilmrlsaqmarrlqvtsekvgnlafldvtgriaqtllnlakqpdamthpdgmqikitrQeigqivgcSRETvgRilkmledqnlisahgktivvygtr