3kjv_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DNA
reference	J.Mol.Biol. 397 967 2010
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3kjv_A interface=87,108,150,176,177,441,468, pispietvpvklkpgmdgpkvkqwkalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnrgrqkvvtltdttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgiggneqvdklvsagi > 3kjv_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfphPaglkkkksvtvldvgdayfsVpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaiFqssmtkilepfrkqnpdiviyqymdDLyvgsdleigqhrtkieelrqhllrelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlek
interface signature	IYPYMRQ/PVFDL

Estimated binding specificities ?

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# IC=3.860 IC/col=0.227 n_of_columns=17

specificity:

A |   8   7   7  24  24  24  24  24  24  24  24  24  24  24  24   7   0
C |   0   7  66  24  24  24  24  24  24  24  24  24  24  24  24  75  96
G |  81   9  22  24  24  24  24  24  24  24  24  24  24  24  24   7   0
T |   7  73   1  24  24  24  24  24  24  24  24  24  24  24  24   7   0

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updated Mon Jan 5 04:38:15 2026