3kk2_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE-DNA COMPLEX WITH DATP BOUND IN THE NUCLEOTIDE BINDING SITE
reference	J.Mol.Biol. 397 967 2010 X-RAY DIFFRACTION
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3kk2_A interface=94,157,183,184,258,356,448,475, pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiCklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnrgrqkvvtltdttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgiggneqvdklvsag > 3kk2_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphPaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaiFqssmtkilepfrkqnpdiviyqymdDLyvgsdleigqhrtkieelrqhllrwglttmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgIkvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteaVqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqle
interface signature	IPYMCRRQ/PFDLIV

Estimated binding specificities ?

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# IC=2.771 IC/col=0.173 n_of_columns=16

specificity:

A |   0   9  24  24  24  24  24  24  24  24  24  24  24  24   1  69
C |   0   9  24  24  24  24  24  24  24  24  24  24  24  24  19   9
G |  96  67  24  24  24  24  24  24  24  24  24  24  24  24  67   9
T |   0  11  24  24  24  24  24  24  24  24  24  24  24  24   9   9

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updated Mon Jan 5 04:39:36 2026