3kk3_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE-DNA COMPLEX WITH GS-9148 TERMINATED PRIMER
reference	J.Mol.Biol. 397 967 2010 C10 H11 F N5 O5 P
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=2.90, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3kk3_A interface=94,157,183,184,258,265,448,475, pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiCklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnrgrqkvvtltdttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgiggneqvdklvsag > 3kk3_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphPaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaiFqssmtkilepfrkqnpdiviyqymdDLyvgsdleigqhrtkieelrqhllrwglyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrQlskllrGtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqle
interface signature	IPYMCNRQ/PFDLQG

Estimated binding specificities ?

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# IC=5.339 IC/col=0.314 n_of_columns=17

specificity:

A |   9   0  24  24  24  24  24  24  24  24  24  24  11  24   9   0   0
C |  11   0  24  24  24  24  24  24  24  24  24  24   9  24   9  96  96
G |  67   0  24  24  24  24  24  24  24  24  24  24  67  24  69   0   0
T |   9  96  24  24  24  24  24  24  24  24  24  24   9  24   9   0   0

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updated Mon Jan 5 04:40:12 2026