3klg_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF AZT-RESISTANT HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO PRE-TRANSLOCATION AZTMP-TERMINATED DNA (COMPLEX N)
reference	Sarafianos et al. Nat.Struct.Mol.Biol. 17 1202 2010
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=3.65, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3klg_A interface=61,74,94,157,183,184,266,448,475, pispietvpvklkpgmdgpkvkqwplteekikalveictelekegkiskigpenpyntpvFaikkknstrwrkLvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglytpdqkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnWasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 3klg_B interface= spietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaIkkkdstkwrklvDfrelnkrtqdfwevqlgipHpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaIfqssmtkilepfkkqnpdiviyqymDDlyvgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlsKllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	FLIPYMWRQ/IDHIDDK

Estimated binding specificities ?

contact

# IC=3.101 IC/col=0.182 n_of_columns=17

specificity:

A |  13  13  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0
C |  13  16  24  24  24  24  24  24  24  24  24  24  24  24  24  96  96
G |  54  13  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0
T |  16  54  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0

scan!

home
updated Mon Jan 5 04:44:37 2026