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structure nameHUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX WITH THE 3'T OF A CPD IN THE ACTIVE SITE (TT1)
(DNA polymerase eta)
referenceRamon-Maiques et al. Nature 465 1044 2010
sourceHomo sapiens
experimentX-ray (resolution=1.75, R-factor=0.188)
structural superfamilyDNA/RNA polymerases;
sequence familyimpB/mucB/samB family;
redundant complexes4dl3 3mr2 3mr5 4dl2 3mr6 4dl5 3si8 4dl4 4eey 3tq1 4dl6 4dl7
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  ----WA--------------------------------STPATATC------LT------RGAC----FT--                           +-----3mr3_A    
                                                                                               +-----4 
  ------------------------------------MANG--------YA----RC--ST------------                     !     +-----3mfi_A    
                                                                                               ! 
  YG------------------------------------EG------RA------------------------       +-------------7      +----3osn_A    
                                                                                 !             !    +-3 
  --VT--AT----PC--------------------ST--------------LA------------RART--RG       !             !    ! !  +-1jx4_A    
                                                                                 !             !    ! +--1 
  ------MASAAAPCIC----------------------EG----------------TG------------RG       !             +----5    +-2oh2_B    
                                                                               --8                  ! 
  ------EG----FG----------------------------------------------------------       !                  !  +---3gqc_A    
                                                                                 !                  +--2 
  --HA--------WG----------------------------------------------------------       !                     +---2aq4_A    
                                                                                 ! 
  --------------------RT--------------------------------------------------       !               +---------3n4m_B    
                                                                                 +---------------6 
  ----------------NGKGNGRTHGKCECNGNG--------------------------------------                       +---------2kn7_A    
                                                                               

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updated Thu Sep 12 17:43:55 2024