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structure nameINHIBITING THE BINDING OF CLASS IIA HISTONE DEACETYLASES TO MYOCYTE ENHANCER FACTOR-2 BY SMALL MOLECULES
referenceJayathilaka et al. 'Nucleic 40 5378 2012
sourceHomo sapiens
experimentX-ray (resolution=2.43, R-factor=?)
structural superfamilySRF-like;
reference complex6wc2_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRK/RK

Estimated binding specificities ?

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# IC=2.938 IC/col=0.294 n_of_columns=10 specificity:   
A |   7   1  56  25  20  24  24  10  73   8
C |  73  20  11  23  22  24  24  16   1   7
G |   8   2  16  21  21  24  24  14  21  65
T |   8  73  13  27  33  24  24  56   1  16
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updated Mon Jan 5 05:44:17 2026