3nbn_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A DIMER OF NOTCH TRANSCRIPTION COMPLEX TRIMERS ON HES1 DNA
reference	Blacklow et al. Nat.Struct.Mol.Biol. 17 1312 2010
source	HOMO SAPIENS
experiment	X-ray (resolution=3.45, R-factor=?)
structural superfamily	DNA-binding protein LAG-1 CSL;p53-like transcription factors;E set domains;
reference complex	3iag_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3nbn_A interface=35,38,40,140,141,145,170,171, pppkrltreamrnylkergdqtvlilhakvaqksYgnEkRffcpppcvylmgsgwkkkkeqmerdgcseqesqpcafigignsdqemqqlnlegknyctaktlyisdsdkrkhfmlsvkmfygnsddigvflskrikviSKpskKkqslknadlciasgtkvalfnrlrSQtvstrylhveggnfhassqqwgaffihlldddesegeeftvrdgyihygqtvklvcsvtgmalprliirkvdkqtalldaddpvsqlhkcafylkdtermylclsqeriiqfqatpcpkepnkemindgaswtiistdkaeytfyegmgpvlapvtpvpvveslqlngggdvamleltgqnftpnlrvwfgdveaetmyrcgesmlcvvpdisafregwrwvrqpvqvpvtlvrndgiiystsltftytpep > 3nbn_D interface=35,38,40,140,141,145,170,171, pppkrltreamrnylkergdqtvlilhakvaqksYgnEkRffcpppcvylmgsgwkkkkeqmerdgcseqesqpcafigignsdqemqqlnlegknyctaktlyisdsdkrkhfmlsvkmfygnsddigvflskrikviSKpskKkqslknadlciasgtkvalfnrlrSQtvstrylhveggnfhassqqwgaffihlldddesegeeftvrdgyihygqtvklvcsvtgmalprliirkvdkqtalldaddpvsqlhkcafylkdtermylclsqeriiqfqatpcpkepnkemindgaswtiistdkaeytfyegmgpvlapvtpvpvveslqlngggdvamleltgqnftpnlrvwfgdveaetmyrcgesmlcvvpdisafregwrwvrqpvqvpvtlvrndgiiystsltftytpep
interface signature	YERSKKSQ/YERSKKSQ

Estimated binding specificities ?

readout + contact

# IC=14.304 IC/col=0.477 n_of_columns=30

specificity:

A |   7   3  11   0   0   3   0  96  80  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  13   0   0  24   3  92
C |  76   6   9   0   0   3   0   0   7  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   7   0  96  24  92   0
G |  10   3  69   0  96  80  96   0   3  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   7   0   0  24   0   4
T |   3  84   7  96   0  10   0   0   6  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  69  96   0  24   1   0

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updated Mon Jan 5 05:48:31 2026