3nbn_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A DIMER OF NOTCH TRANSCRIPTION COMPLEX TRIMERS ON HES1 DNA
reference	Blacklow et al. Nat.Struct.Mol.Biol. 17 1312 2010
source	HOMO SAPIENS
experiment	X-ray (resolution=3.45, R-factor=?)
structural superfamily	DNA-binding protein LAG-1 CSL;p53-like transcription factors;E set domains;
reference complex	3iag_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3nbn_A interface=35,38,40,140,141,145,170,171, pppkrltreamrnylkergdqtvlilhakvaqksYgnEkRffcpppcvylmgsgwkkkkeqmerdgcseqesqpcafigignsdqemqqlnlegknyctaktlyisdsdkrkhfmlsvkmfygnsddigvflskrikviSKpskKkqslknadlciasgtkvalfnrlrSQtvstrylhveggnfhassqqwgaffihlldddesegeeftvrdgyihygqtvklvcsvtgmalprliirkvdkqtalldaddpvsqlhkcafylkdtermylclsqeriiqfqatpcpkepnkemindgaswtiistdkaeytfyegmgpvlapvtpvpvveslqlngggdvamleltgqnftpnlrvwfgdveaetmyrcgesmlcvvpdisafregwrwvrqpvqvpvtlvrndgiiystsltftytpep > 3nbn_D interface=35,38,40,140,141,145,170,171, pppkrltreamrnylkergdqtvlilhakvaqksYgnEkRffcpppcvylmgsgwkkkkeqmerdgcseqesqpcafigignsdqemqqlnlegknyctaktlyisdsdkrkhfmlsvkmfygnsddigvflskrikviSKpskKkqslknadlciasgtkvalfnrlrSQtvstrylhveggnfhassqqwgaffihlldddesegeeftvrdgyihygqtvklvcsvtgmalprliirkvdkqtalldaddpvsqlhkcafylkdtermylclsqeriiqfqatpcpkepnkemindgaswtiistdkaeytfyegmgpvlapvtpvpvveslqlngggdvamleltgqnftpnlrvwfgdveaetmyrcgesmlcvvpdisafregwrwvrqpvqvpvtlvrndgiiystsltftytpep
interface signature	YERSKKSQ/YERSKKSQ

Estimated binding specificities ?

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# IC=13.191 IC/col=0.440 n_of_columns=30

specificity:

A |   4   0  24   0  96  66  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0   0   4   0  96  24  84   8
C |   4   1  24   0   0  14  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   8   0  96  79  96   0  24   4   8
G |   1  91  24  96   0   8  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   9   0   0   9   0   0  24   4  70
T |  87   4  24   0   0   8  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  75  96   0   4   0   0  24   4  10

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updated Fri Dec 13 16:41:42 2024